NEFL and nervous system disorder: NfL is a promising diagnostic and prognostic fluid biomarker with high translational value in many neurological disorders.[36, 37, 38] Due to its convenience and lesser invasiveness in clinical practice, blood NfL measurement has been an exciting and active field of research.[36, 39] Idiopathic PD and atypical parkinsonisms are different in the clinical course, prognosis, and therapy needs.