POMC and adrenal gland hyperfunction: The following exclusion criteria were applied: active malignancies, bilateral micro- or macronodular adrenal hyperplasia, maximum diameter of AI ≤1 cm, primary hyperaldosteronism, pheochromocytoma, suspected adrenocortical carcinoma or adrenal metastases, adrenal pseudocysts or myelolipomas, AdrenoCorticoTropic Hormone (ACTH)-dependent hypercortisolism, presence of signs or symptoms of overt hypercortisolism, steroid or gonadal therapy, or other drugs interfering with cortisol determination after a dexamethasone suppression test.