APOBEC3A and oropharynx cancer: For example, higher expression levels of APOBEC3A can be induced by HPV16 infection in oropharyngeal cancer,62 while APOBEC3A protein levels were downregulated during invasive progression in HPV‐negative but not HPV‐positive penile squamous cell carcinomas, suggesting that HPV‐associated APOBEC3A activity is variable and context‐dependent.63