Vitamin D may be associated with cardiovascular health and cardiovascular physiology and pathology through multiple pathways, as noted by Normal et al49 and Al Mheid el al,50 which include regulations of myocyte proliferation and hypertrophy51 and the renin-angiotensin system.52 Vitamin D also may be a factor in implantation, placentation, and angiogenesis processes and is essential for maintaining a healthy pregnancy.53,54 Mechanisms on how vitamin D may modify the association between preeclampsia and child BP, however, is unclear. The gene discussed is REN; the disease is preeclampsia.