Lu et al. [24] concluded that IL-6 genotypes of rs1800795 GC and rs1800796 GG might point to a relatively high risk for T2DM patients suffering from proliferative diabetic retinopathy in a Chinese population and which was associated with elevation of IL-6 expression in both mRNA and protein, but the sample was also too small (215 cases of T2DM with proliferative diabetic retinopathy and 207 cases of T2DM with a normal retinal function) and without normal controls. Here, IL6 is linked to proliferative diabetic retinopathy.