CNR1 and anterior segment dysgenesis: To understand whether the impairment of eCB signaling is a shared pathological event between ASMD and NPC, and whether enhancement of this system could be considered as a common therapeutic strategy for this and potentially other sphingolipid storage disorders, we analyzed CB1 levels in the brain of an NPC mouse model and a patient, as well as the effects of FAAHi in NPC patient‐derived cells and the NPC mouse model.