NFKB1 and neoplasm: The upregulation of miR-233 was demonstrated in several studies, using different in vitro experiments, with HCT116, SW620 cell lines, or other tumor cell lines or primary tissues [139–141] The overexpression of miR-233 was found to promote cancer cell proliferation and silenced FoxO3a through NF-κB activation and upregulation of the inflammasome complexes [139], together with miR-22 which was also expressed but in lower levels in colorectal condition [94].