HMGB1 and osteosarcoma: The metastasis-free survival rate of the high lncR-C3orf35/HMGB1 expression group was lower than that of the low lncR-C3orf35/HMGB1 expression group (lncR-C3orf35: p = 0.01; HMGB1: p = 0.04), which indicated that lncR-C3orf35/HMGB1 was correlated with osteosarcoma metastasis.