TP53 and cancer: Further analysis by gene set enrichment analysis (GSEA) showed that the p53, cell cycle, cell adhesion junction, PI3K-AKT-mTORC, Notch, TGFβ, epithelial-mesenchymal transition (EMT), and other cancer-related signaling pathways were enriched in the tumors, which was in accordance with previous studies (Figures 1(c)–1(e) and Supplementary Figure 2A-L).