T cell chemokine CXCL10 has also been associated with Cryptococcus infections; during murine infection with C. gattii, a close pathogenic relative to C. neoformans, an impaired TH1 migration in the lung is correlated with decreased Ip10 expression and poor DC maturation when compared to C. neoformans infection, leading to an attenuated effector T cell response and increased pulmonary infection (89). The gene discussed is CXCL10; the disease is infection.