CXCL10 and infection: The modulation of neutrophil recruitment is not limited to S. aureus-derived soluble factors, as S. pneumoniae-derived virulence factor PepO is found to contrastingly increase secretion of chemoattractants CXCL8 and IP-10 (CXCL10) from bronchial cell line BEAS-2B, suggesting that this factor may increase recruitment of neutrophils to the site of infection (88).