VEGFA and decubitus ulcer: Fujiwara et al. (2020) also constructed an ovine burn model and proved that ASCs improved grafted burn wound healing by promoting blood flow and vascular endothelial growth factor (VEGF) expression. Besides, the localized injection of ASCs could accelerate and enhance the closure of pressure ulcers (Xiao et al., 2019). Likewise, Bukowska et al. (2020) systematically ensured the safety of human SVF when injected into a murine pressure ulcer injury model.