YWHAQ and Parkinson disease: Finally, a recent study pinpoints 14-3-3 proteins as potential regulators of α-synuclein transmission, proposing that they normally prevent α-synuclein oligomerization and resultant toxicity, whereas 14-3-3 protein dysfunction mediates α-synuclein oligomerization and seeding, that govern PD pathology (Wang et al., 2018).