SNP variance in miR-146a precursor rs2910164 was related to anti-TNF-a treatment in rheumatoid arthritis (RA) patients (Bogunia-Kubik et al., 2016) and also affected phenotypes in breast cancer (BC; Meshkat et al., 2016) and the progression of cervical cancer (Hu et al., 2018). The gene discussed is TNF; the disease is breast cancer.