Figure 7B showed the representative xenograft tumors, which indicated that average tumor weights of miR-497 group was decreased by 70%. Total RNAs and proteins in tumor samples were analyzed by qRT-PCR and Immunoblotting, which showed that miR-497 repressed expression of AKT2 in tumor tissues (Figures 7C,D). This evidence concerns the gene AKT2 and neoplasm.