In another study of 413 school children with asthma, those that experienced at least one exacerbation irrespective of RV infection were more likely to possess Moraxella-dominated nasal microbiota composition (112) and elevated eosinophil cationic protein concentration in nasal secretions (a marker for activated eosinophils)—suggesting that such microbial communities may promote asthma exacerbation in the absence of RV. Here, RNASE3 is linked to asthma.