CYBB and gastric cancer: In the present study, PPI and WGCNA networks revealed 6 common hub genes, including PTPRC, TYROBP, CCR1, C1QB, CYBB, and LCP2. According to Wang et al. (39), CYBB is associated with invasion and prognosis of human gastric cancer, whereas PTPRC, also known as CD45, has been previously used to assess the extent of immune cell infiltration in intestinal-type Japanese gastric cancer (40).