CASP3 and non-small cell lung carcinoma: Given the fact that both cordycepin and apatinib significantly induced the apoptosis of NSCLC cells, we used western blotting to evaluate the expression of related proteins in apoptotic signaling pathways including VEGFR2, VEGF, p-PI3K, PI3K, Akt, p-Akt, Caspase-3, Cleaved Caspase-3, Bax, and Bcl-2.