Clinically, plerixafor, in combination with granulocyte colony-stimulating factor (G-CSF), has proven effective for the mobilization of hematopoietic stem cells in patients with multiple myeloma (MM) and non-Hodgkin's lymphoma (NHL) undergoing autologous stem cell transplantation (53). The gene discussed is CSF3; the disease is non-Hodgkin lymphoma.