CD274 and non-small cell lung carcinoma: Nivolumab plus ipilimumab as first-line therapy in advanced NSCLC can be cost-effective compared with chemotherapy if the cost of nivolumab was cut by 21% or the cost of ipilimumab down by 24% in patients with a PD-L1 expression <1% at a WTP threshold of $150,000 per QALY.