Nonetheless, the bSRS was superior in differentiating prognostic OS subgroups compared to all other indexes as indicated by the higher c-index and the properly separated Kaplan–Meier curves (Figures 1–3), since it reflects the latest knowledge of prognostic OS factors in treatment of limited brain metastases in breast cancer patients, namely, KPS, Her2/neu positivity, and extracranial control (Tables 1, 7). Here, ERBB2 is linked to breast carcinoma.