It has been reported that EZH2 recruits LINC00673 (17, 25–27), and it is reasonable to consider that EZH2 is recruited to the CDKN2C promoter by LINC00673, increasing the level of H3K27me3 to regulate CDKN2C expression and, thus, affecting the proliferation of ESCC cells (Figures 7A,B). The gene discussed is LINC00511; the disease is esophageal squamous cell carcinoma.