<b>Purpose:</b> To evaluate the accuracy of <sup>68</sup>Ga-PSMA positron emission tomography/computerized tomography (PET/CT) for preoperative lymph node staging using histopathological results of pelvic lymph node dissection (PLND) as reference standard in patients with intermediate/high risk of prostate cancer. The gene discussed is FOLH1; the disease is Familial prostate cancer.