For example, secretory meningiomas show frequent co-mutations of the KLF4 and TRAF7 genes (13, 14), while clear cell meningiomas show SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin, subfamily e, member 1 (SMARCE1) mutations (15). This evidence concerns the gene KLF4 and meningioma.