In particular, CCL21 chemoattracting dendritic cells and T lymphocytes are critical in initiating a T-cell response73, while CCL2 attracts monocytes or macrophages and CXCL9 recruits T cells and NK cells74, confirming the moderating effect on immunosuppression in the tumour microenvironment induced by the combination treatment of BP and aCD47. The gene discussed is CCL21; the disease is neoplasm.