In particular, CCL21 chemoattracting dendritic cells and T lymphocytes are critical in initiating a T-cell response73, while CCL2 attracts monocytes or macrophages and CXCL9 recruits T cells and NK cells74, confirming the moderating effect on immunosuppression in the tumour microenvironment induced by the combination treatment of BP and aCD47. This evidence concerns the gene CXCL9 and neoplasm.