CASP4 and non-small cell lung carcinoma: In our experimental conditions, tissue levels of both caspase-4 and LDH dissected NSCLC patients in a smaller subpopulation (47.3%), implying on one side that LDH and caspase-4 are not strictly correlated at the tissue levels, but on the other that caspase-4 is not able to induce cell death in the tumor tissue.