NFKB1 and Anxiety: Its proinflammatory toxicity is related to Pinellia pedatisecta lectin (PPL), which activates the reactive oxygen species (ROS)/mitogen-activated protein kinase (MAPK)/nuclear factor kappa-B (NF-κB) pathway and NOD-like receptor protein 3 (NLRP3) inflammasome [42].The ingredients in the compounds also include benzodiazepines, which the main effects are sedation, hypnosis, and decreased anxiety [43].This is likely to be the mechanism by which HJZT promotes sleep in mice.