The further development of inflammation may lead to liver fibrosis, and total flavonoids of PCP significantly inhibited the decrease of body mass and mitigated further development of liver fibrosis in alcohol rats, then elevated liver coefficient, decreased serum hyaluronic acid (HA), laminin (LN), type III pre-collagen (PCIII) levels, and the content of Hyp in liver tissue, and reduced serum TNF-α, IL-6 levels. The gene discussed is LAMB2; the disease is Hepatic fibrosis.