Moreover, KEGG pathway enrichment analysis results indicated that IRGs in the relevant module were involved in natural killer cell mediated cytotoxicity, primary immunodeficiency, T cell receptor signaling pathway, cytokine–cytokine receptor interaction, Th1 and Th2 cell differentiation, Th17 cell differentiation, viral protein interaction with cytokine and cytokine receptor, human T-cell leukemia virus 1 infection, antigen processing and presentation, PD-L1 expression, and PD-1 checkpoint pathway in cancer (Figure 6B). The gene discussed is CD274; the disease is cancer.