In I-type tumors, remoteness of cancer cells to CD68+ macrophages, pDCs and CD123+CD15+ granulocytes was significantly associated with a shorter OS in adjusted analysis (HR = 2.35, 95% CI 1.01–5.49, HR = 3.32, 95% CI 1.08–10.21 and HR = 5.29 95% CI 1.19–23.43, respectively), whereas in PB type tumors, remoteness of cancer cells to CD123+CD15+ granulocytes (HR = 0.30, 95% CI 0.14–0.64) was significantly associated with a prolonged OS in adjusted analysis. Here, CD68 is linked to cancer.