Furthermore, we explored the urinary levels of LRG1, ORM1, and ORM2 in patients with AOSD, rheumatoid arthritis (RA), neoplasms, and infections and healthy control (HC) subjects by enzyme-linked immunosorbent assay (ELISA) and determined the correlation between the urinary levels of LRG1, ORM1, and ORM2 and clinical symptoms of AOSD. The gene discussed is ORM1; the disease is neoplasm.