The results in Figure 2D showed that the AUC of LRG1 was 0.700 (p = 0.000), the AUC of ORM1 was 0.837 (p = 0.000), and the AUC of ORM2 was 0.736 (p = 0.000), and a three-panel combined AUC was 0.838 (p = 0.000; Supplementary Table 2), suggesting that these three urinary proteins, especially ORM1, could be used as diagnostic markers for AOSD. Here, ORM1 is linked to adult-onset Still disease.