CXCL12 and neoplasm: In addition, various migratory cues have been identified to direct pDCs from BM into the blood or diseased tissues including tumor-derived CXCL12 (SDF-1), CXCR3 ligands CXCL9/10 and CCR7 ligands CCL19 and CCL21 (6, 9, 42–47).