▪ There are significant differences in IFN-γ responses for DosR antigens (Rv1735c, Rv2006, Rv2625c, Rv1996, Rv2032, Rv2629, Rv3126c, Rv0081, Rv2631, Rv3130c, Rv2624c, Rv2007c, Rv2028c, and Rv3134) in healthy household contacts compared with patients with active TB, as reported by a study in whole blood that included a wide range of stage-specific antigens to assess IFN-γ response in a long-incubation assay (65). The gene discussed is IFNG; the disease is tuberculosis.