LGALS3 and neoplasm: Because Gal-3 is a key molecule involved in several aspects of tumor progression and metastasis (10), and our previous data suggested that TPIN-SCs over-express the Gal-3 transcript (29, 30), here we further investigated the expression of Gal-3 in TPIN-SCs, and asked if Gal-3 expressed by prostate CSCs plays a relevant role in the neoplastic process.