BACH2 and PAX5 expression was also lower in MR patients compared to NR patients (BACH2: 1.0 ± 0.0, 3.9 ± 2.0, and 0.9 ± 0.3 fold difference; PAX5: 1.0 ± 0.0, 3.5 ± 1.7, and 0.9 ± 0.2 fold difference for HC, NR, and MR respectively; p < 0.001, MR compared with NR, for both) (Figure 2D). The gene discussed is BACH2; the disease is miotic rate.