While there were no virulence factors found frequently and exclusively in the UTI isolates, the E. coli laminin-binding fimbriae (ELF) and non-LEE type III secretion system effector (TTSS) virulence factors were often present (30 and 40%, respectively) in UTI isolates and absent in all of the no LUTS isolates. Here, SPTBN1 is linked to bacterial urinary tract infection.