TRPV2 and myocardial infarction: Furthermore, both TRPV1 and V2 contribute to the inflammatory response following MI; however, mice harboring a global deletion of TRPV1 show an exacerbated inflammatory response 3- and 7-days post-MI whereas mice with a global knockout of TRPV2 show improved cardiac recovery following MI due to a reduction in peri-infarct macrophages (Huang et al., 2009; Entin-Meer et al., 2017; Falcon et al., 2019).