In addition, asiatic acid can induce the dissipation of mitochondrial membrane potential (MMP), ATP depletion, release of cytochrome c from mitochondria into the cytosol of HepG2 cells, which may induce the death of liver cancer cells by directly affecting mitochondrial function, it may be a potential therapeutic drug for liver cancer and colon cancer (Lu et al., 2016; Hao et al., 2018). Here, CYCS is linked to malignant colon neoplasm.