NFKB1 and acute respiratory distress syndrome: As for asiaticoside, the review found that it can reduce the inflammatory infiltration caused by lipopolysaccharide in a dose-dependent manner, and inhibit the inflammatory response in lung tissue by inhibiting the NF-κB signaling pathway(TNF-α ↓, IL-6 ↓, p-IκB ↓, p-p65 ↓), which can be an effective preventive agent for ALI (Qiu et al., 2015).