NFE2L2 and Cognitive impairment: Previous studies found that C. asiatica and its triterpenoids could effectively increase SOD and GPX activities, activate nuclear factor erythroid-2-related factor 2, improve the cognitive impairment of animals, and then alleviate the symptoms of related diseases (Gray et al., 2017a; Chintapanti et al., 2018; Welbat et al., 2018).