TLR2 expression is up-regulated in oligodendrocytes, peripheral blood mononuclear cells, cerebrospinal fluid mononuclear cells, and demyelinating lesions of MS patients (Miranda-Hernandez and Baxter, 2013; Hasheminia et al., 2014; Hossain et al., 2018). The gene discussed is TLR2; the disease is myeloid sarcoma.