EGFR and cancer: Activation and mutations of PI3 kinase (PI3K), mTOR, insulin-like growth factor (IGF-1), epidermal growth factor receptor (EGFR), and NF-κB pathways have all been identified in several human disorders (Lewis et al., 2018; Souder and Anderson, 2019; Carter et al., 2019; Farias Quipildor et al., 2019), especially cancer (Hanahan and Weinberg, 2011; Royce et al., 2019).