Studies have shown that survivin is dramatically overexpressed in various of tumors, such as breast cancer, colon cancer, and lung cancer, and promotes the proliferation and metastasis of tumor cells (Kawasaki et al., 1998; Monzo et al., 1999; Suzuki et al., 2000; Tanaka et al., 2000; Marioni et al., 2006; McKenzie et al., 2010; Kedinger et al., 2013; Ma et al., 2016; Yang et al., 2016; Liu et al., 2019). The gene discussed is BIRC5; the disease is breast cancer.