In the experiment, asthma group showed a dose-dependent decline in Cydn (Figure 2B) and an increase in RL at Mch dose of 6.25 (p = 0.068) and 12.5 mg/ml (p < 0.001) (Figure 2A) compared with normal control group, which revealed that mice exposed to OVA have developed significant AHR. Here, AHR is linked to asthma.