Expression of autophagy-related molecules LC3 and Beclin1 was down-regulated in ectopic and eutopic ESCs of patients with endometriosis compared to that in the ESCs of patients with leiomyoma, and the expression of LC3 and Beclin1 in ectopic ESCs was also significantly lower than that in eutopic ESCs. The gene discussed is BECN1; the disease is leiomyoma.