In view of NLRC5 co-localized with LC3 and Beclin1 in nucleus in EESCs from patients with endometriosis, furthermore, NLRC5 led to the expressions of LC3 and Beclin1, we speculate that NLRC5 may promote autophagy by activating autophagy protein Beclin1 or other ATGs, which need to be validated in the future. Here, NLRC5 is linked to endometriosis.