MAPK14 and amyotrophic lateral sclerosis: Increased activity of stress-activated MAP kinase was detected in cortical neurons of an ALS mouse model (Holasek et al., 2005) while higher p-p38 levels have been detected in human post-mortem ALS brains (Krieger et al., 2003; Sama et al., 2017) and mouse models of ALS (Tortarolo et al., 2003; Holasek et al., 2005; Veglianese et al., 2006; Sama et al., 2017).