MoCA score was considered the dependent variable, and age, sex, education level, diabetes duration, insulin use, BMI, HbA1c, FBG, PBG, TC, TG, LDL-C, HDL-C, ApoA1, ApoB, and sLRP1 were considered the independent variables in the multiple linear regression analysis. This evidence concerns the gene APOA1 and diabetes mellitus.