Based on the connection between higher levels of lncRNA SLC7A11-AS1 or hsa_circ_0006123 and vascular invasion in HCC patients, we further assessed the possible roles of lncRNA SLC7A11-AS1 and hsa_circ_0006123 in modulating HCC cell migration and invasion. The gene discussed is SLC7A11; the disease is hepatocellular carcinoma.