As shown in Fig. 5f–h, although the tumor weight was not significantly different between the EV + DMSO and B7-H3 + DMSO groups, subcutaneous xenografts in the B7-H3 + DMSO group grew significantly faster than those in the EV + DMSO group following 10 Gy X-ray irradiation, whereas cotreatment with SB743921 and irradiation further suppressed tumor growth and tumor weight. The gene discussed is CD276; the disease is neoplasm.