To identify whether the TME‐related signature is an independent predictive factor for GBM patients, the probable predictors, age group (young vs. old), CIMP status (non–G‐CIMP vs. G‐CIMP), MGMT status (unmethylated vs. methylated), subtype (neural + preneural vs. mesenchymal + classical) and risk level (low vs. high) were analysed by univariate and multivariate Cox proportional hazard regression. The gene discussed is MGMT; the disease is glioblastoma.