MGMT status (HR = 1.39, P = .017), CIMP status (HR = 3.04, P = .003), age group (HR = 0.63, P = .001) and risk level (HR = 0.53, P = .004) were found to be independent predictors in the TCGA GBM data set. The gene discussed is MGMT; the disease is glioblastoma.