Furthermore, LCP1, ADPGK, and LCP1+ADPGK successfully predicted pneumonitis in 26 lung cancer patients with AUC as 0.74, 0.76, and 0.77, respectively (Supplementary Fig. 12), suggesting the potential utility of LCP1 and ADPGK in predicting a specific type of irAE in a specific cancer. This evidence concerns the gene ADPGK and lung carcinoma.