We found that genes associated with response to heat shock (hsp-16, hsp-70), metal (numr and cdr), and infection (irg-1, -2), as well as glutathione S-transferases (gst), several DAF-16 target genes (dod-22, -17, -24), and PQM-1/DAF-16 regulated targets (C32H11 and F55G11)14 are upregulated, indicating that the animals are responding to stress conditions. The gene discussed is ACOD1; the disease is infection.