We also detected the function of SNHG1 on HCC cell growth by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assays and the result suggested that SNHG1 knockdown inhibited cell growth significantly and SNHG1 overexpression promoted cell growth (Supplementary Fig. S3a, b). The gene discussed is SNHG1; the disease is hepatocellular carcinoma.